Yes, so, um, you know, as I, I think we're gonna learn a lot about, um, this, uh, class of medications. Uh, the longer the patient, the more patient experience that we have with it. I, it's, again, it's not a drug that, uh, causes any immediate, you know, one-week improvement. You really have to, uh, explain to the patient that there is this kind of twelve-week, uh, of onset, um, for the effectiveness of the drug and the airways. So, um, I think we're, we just have to closely monitor the patients that were starting, uh, rencicatib in terms of obviously their day to day symptoms, um, but also, um, the exacerbation frequency. You need to have them check in with you if they think they're having an exacerbation. And then, um, you know, finally, the looking at their lung function over time. You know, the other question with this medication, um, both the 10 and the 25 mg doses were approved by the FDA, and it, it is challenging to know, um, which dose is right for your particular patient. It's really doesn't appear to be a weight-based um decision or an age-based decision, and, and there's no real drug interactions that we're aware of, so you're really open to prescribing either. Um, those secondary endpoints did look better in the higher dose, um, but it's really gonna be our phase 4, you know, post-marketing experience with the drug that's gonna help us determine ultimately, Um, if there is a significant difference between the two doses and the overall, uh, outcomes of the patients.
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